Graduate Students

About the graduate students:

We consider neither the scientific nor the translational potential towards ‘resolution of inflammation’ to be sufficiently exploited. Therefore, young researchers need to be specifically educated in this field. This will enable them to explore mediators and principles of resolution of inflammation in academia, the clinics, and pharmaceutical industry. To this end, graduates in biology, biochemistry, immunology, pharmacology, pharmacy, and molecular medicine have been recruited to AVE through a rigid evaluation process. Together with associated PhD candidates and medical students, they will tackle the questions raised within the three scientific clusters of AVE.

Currently we are educating the second cohort in our 3x 3 years programme.
To have a look on our Alumni click here.

Cluster 1:

Project 1

Anastasiia Kiprina

Anastasiia Kiprina
Master of Science, Biology

PhD-Thesis: Mechanisms of IL-38 signaling in inflammation and cancer

Thesis Committee: Supervisor: Prof. Dr. Andreas Weigert

Co-Supervisor: Prof. Dr. Bernhard Brüne

Contact: Institute of Biochemistry 1
Goethe-University Frankfurt
Email address:

www.pathobiochemie1.de

Project 3

Jessica Raith

Jessica Raith
Pharmacist

PhD-Thesis: Non-hepatic organ-to-liver cross communication in the pathophysiology and resolution of acetaminophen-induced liver injury

Thesis Committee: Supervisor: Prof. Dr. Heiko Mühl

Co-Supervisor: Prof. Dr. Ellen Niederberger
Prof. Dr. Andreas Weigert

Contact: Institute of General Pharmacology and Toxicology
Goethe-University Frankfurt
Email address:

www.pzf.de/allg

Associate

Camilla Tondello

Camilla Tondello
Master of Science,
Pharmaceutical Chemistry and Technology

PhD-Thesis: Blockade of the XCL1/XCR1 chemokine axis as a type 1 diabetes therapy

Thesis Committee: Supervisor: Prof. Dr. Urs Christen

Co-Supervisor: Prof. Dr. Klaus Scholich

Contact: Institute of General Pharmacology and Toxicology
Goethe-University Frankfurt
Email address:

www.pzf.de/allg

Associate

Ioanna Tsoukala

Ioanna Tsoukala
Master of Science,
Technical Biology

PhD-Thesis: Exploring the mechanisms of immune-supression in leukemia

Thesis Committee: Supervisor: Dr. Hind Medyouf

Co-Supervisor: Prof. Dr. Andreas Weigert

Contact: Georg-Speyer-Haus
Email address:

www.georg-speyer-haus.de

Associate

Xin You

Xin You
Physician,
medical scientist

PhD-Thesis: PhD-Thesis: The role of interleukin 38 (IL-38) in inflammatory colon carcinogenesis

Thesis Committee: Supervisor: Prof. Dr. Andreas Weigert

Co-Supervisor: Prof. Dr. Heiko Mühl

Contact: Institute of Biochemistry 1
Goethe-University Frankfurt
Email address:

www.pathobiochemie1.de

Associate

Anna Schwantes

Anna Schwantes
Pharmacist

PhD-Thesis: Macrophages in sensing and executing Ferroptosis

Thesis Committee: Supervisor: Prof. Dr. Bernhard Brüne

Co-Supervisor: Prof. Dr. Andreas Weigert

Contact: Institute of Biochemistry 1
Goethe-University Frankfurt
Email address:

www.pathobiochemie1.de

Associate MD

Michelle Seifert

Michelle Seifert
Master of Science,
Biomolecular Engineering

PhD-Thesis: Development of molecular strategies for the lysosomal degradation of target proteins

Thesis Committee: Supervisor: Dr. Schara Safarian

Co-Supervisor: Prof. Dr. Heiko Mühl Contact

Contact: Fraunhofer Institut für Translationale Medizin und Pharmakologie (ITMP)
Goethe-University Frankfurt
Email address:

https://www.itmp.fraunhofer.de/

Associate MD

Julia Heinen

Julia Heinen
Medical Student

MD-Thesis: Modelling pro vs anti-tumor functions of neutrophils in organoid cultures

Thesis Committee: Supervisor: Prof. Dr. Andreas Weigert

Contact: Institute of Biochemistry 1
Goethe-University Frankfurt
www.pathobiochemie1.de

Cluster 2:

Project 4

Marcel Müller

Marcel Müller
Pharmacist

PhD-Thesis: Transcellular biosynthesis of pro-resolving lipid mediators (SPM) in co-incubations of macrophages with dying neutrophils

Thesis Committee: Supervisor: Prof. Dr. Dieter Steinhilber
Dr. Astrid Kahnt

Co-Supervisor: tba

Contact: Institute of Pharmaceutical Chemistry
Goethe-University Frankfurt
Email address:

www.uni-franfurt.de/53483647/Steinhilber

Project 5

Ürün Ukan

Ürün Ukan
Master of Science, Biotechnology

PhD-Thesis: Role of soluble epoxide hydroxylase (sEH) in macrophagepolarization and resolution of Inflammation

Thesis Committee: Supervisor: Prof. Dr. Ingrid Fleming

Co-Supervisor: Prof. Dr. Andreas Weigert

Contact: Institute of Vascular Signalling
Goethe-University Frankfurt
Email address:

www.vrc.uni-frankfurt.de

Project 6

Sylvia Rösser

Silvia Rösser
Master of Science,
Molecular Medicine

PhD-Thesis: Translational regulation of the resolution of inflammation in macrophages

Thesis Committee: Supervisor: PD Dr. Tobias Schmid
Prof. Dr. Bernhard Brüne

Co-Supervisor: Dr. Hind Medyouf

Contact: Institute of Biochemistry 1
Goethe-University Frankfurt
Email address:

www.pathobiochemie1.de

Project 7

Joschua Friedel

Joschua Friedel
Master of Science, Biology

PhD-Thesis: Role of mast cell-derived mediators during resolution of inflammation

Thesis Committee: Supervisor: Prof. Dr. Klaus Scholich

Co-Supervisor: Prof. Dr. Ellen Niederberger

Contact: Institute of Clinical Pharmacology
Goethe-University Frankfurt
Email address:

www.kgu.de/zpharm/klin

Project 8

Eleonora Mungo

Eleonora Mungo
Master of Science,
Molecular Bioscience

PhD-Thesis: The impact of IKKε inhibition on the velocity of atherosclerosis progression: Do T-cells play a role?

Thesis Committee: Supervisor: Prof. Dr. Ellen Niedernberger

Co-Supervisor: Prof. Dr. Heiko Mühl

Contact: Institute of Clinical Pharmacology
Goethe-University Frankfurt
Email address:

www.kgu.de/zpharm/klin

Project 12

Joshua Kandler

Joshua Kandler
Master of Science, Molecular Biotechnology

PhD-Thesis: SARS-CoV-2 infection in monocytes/macrophages: pattern of inflammation and its resolution

Thesis Committee: Supervisor: Prof. Dr. Denisa Bojkova

Co-Supervisor: Prof. Dr. Andreas Weigert

Contact: Institute of Medicinal Virology,
University Hospital Frankfurt
Email address:

www.kgu.de/einrichtungen/institute/zentrum-der-hygiene/medizinische-virologie/

Associate

Vanesa Guerrero Ruiz

Vanesa Guerrero Ruiz
Master of Science, Immunology

PhD-Thesis: Macrophage lipid metabolism in the tumour microenvironment

Thesis Committee: Supervisor: Prof. Dr. Andreas Weigert

Co-Supervisor: Prof. Dr. Bernhard Brüne

Contact: Institute of Biochemistry 1
Goethe-University Frankfurt
Email address:

www.pathobiochemie1.de

Associate

Anja Kolbinger

Anja Kolbinger
Master of Science,
Human- and Molecular biology

PhD-Thesis: The organization of microenvironments by eosinophil granulocytes and macrophages during local inflammation

Thesis Committee: Supervisor: Prof. Dr. Klaus Scholich

Co-Supervisor: Prof. Dr. Andreas Weigert

Contact: Institute of Clinical Pharmacology
Goethe-University Frankfurt
Email address:

www.kgu.de/zpharm/klin

Associate

Sofie Meyer

Sofie Meyer
Master of Science,
Molecular Medicine

PhD-Thesis: IFN signalling in the hypoxic tumor microenviroment

Thesis Committee: Supervisor: PD Dr. Tobias Schmid

Co-Supervisor: Prof. Dr. Andreas Weigert

Contact: Institute of Biochemistry 1
Goethe-University Frankfurt
Email address:

www.pathobiochemie1.de

Associate

Michelle Haß

Michelle Haß Pharmacist

PhD-Thesis: The role of IKKε in T-cell-regulation in melanoma

Thesis Committee: Supervisor: Prof. Dr. Ellen Niedernberger

Co-Supervisor: Prof. Dr. Andreas Weigert
Prof. Dr. Heiko Mühl

Contact: Institute of Clinical Pharmacology
Goethe-University Frankfurt
Email address:

www.kgu.de/zpharm/klin

Associate MD

Bethy Bezuneh

Bethy Bezuneh Medical student

MD-Thesis: Functional characterization of inflammation-regulated endothelial microproteins

Thesis Committee: Supervisor: Prof. Ingrid Fleming

Contact: Institute of Vascular Signalling
Goethe-University Frankfurt
www.vrc.uni-frankfurt.de

Associate MD

Milou Heffels

Milou Heffels
Medical Student

MD-Thesis: ALOX15B in the glioblastoma microenvironment

Thesis Committee: Supervisor: PD Dr. Tobias Schmid

Contact: Institute of Biochemistry 1
Goethe-University Frankfurt
www.pathobiochemie1.de

Associate MD

Yuwei Du

Yuwei Du
Medical Student

MD-Thesis: Pro-resolving mediators in mast cells

Thesis Committee: Supervisor: Prof. Dr. Klaus Scholich

Contact: Institute of Clinical Pharmacology
Goethe-University Frankfurt
https://www.kgu.de/zpharm/klin/

Cluster 3:

Project 9

Sarah Ciurus

Sarah Ciurus
Master of Science, Molecular Biology

PhD-Thesis: Characterization of the kinase inhibitor C81 during resolution of inflammation

Thesis Committee: Supervisor: Prof. Dr. Robert Fürst

Co-Supervisor: Prof. Dr. Andreas Weigert

Contact: Institute of Pharmaceutical Biology
Goethe-University Frankfurt
Email address:

www.uni-frankfurt.de/53344830/
Institut_für_Pharmazeutische_Biologie

Project 10

Tom Teichmann

Tom Teichmann
Master of Science,
Pharmaceutical Biotechnology

PhD-Thesis: The nuclear Corepressor NCoR1 and its physiological role in the vascular system

Thesis Committee: Supervisor: Prof. Dr. Ralf Brandes

Co-Supervisor: Prof. Dr. Robert Fürst

Contact: Institute of Cardiovascular Physiology
Goethe-University Frankfurt
Email address:

www.vrc.uni-frankfurt.de

Project 11

Jennifer Zimmermann

Jennifer Zimmermann
Master of Science, Molecular Biomedicine & Genome Biology

PhD-Thesis: The role of P2X4 in inflammation, regeneration and tumorigenesis

Thesis Committee: Supervisor: Prof. Dr. Florian Greten

Co-Supervisor: Prof. Dr. Andreas Weigert

Contact: Georg-Speyer-Haus
Email address:

www.georg-speyer-haus.de

Associate

Thomas Zech

Thomas Zech
Pharmacist

PhD-Thesis: The effect of the carbazole derivative C81 on angiogenic processes in the endothelium

Thesis Committee: Supervisor: Prof. Dr. Robert Fürst

Co-Supervisor: Prof. Dr. Dieter Steinhilber

Contact: Institute of Pharmaceutical Biology
Goethe-University Frankfurt
Email address:

http://www.uni-frankfurt.de/53344830/
Institut_für_Pharmazeutische_Biologie

Associate

Philipp Reus

Philipp Reus
Master of Science, Toxicology

PhD-Thesis: Establishment of new antiviral therapy approaches against SARS-CoV-2

Thesis Committee: Supervisor: Prof. Dr. Sandra Ciesek

Co-Supervisor: Prof. Dr. Dieter Steinhilber

Contact: Institute of Medicinal Virology,
University Hospital Frankfurt
Email address:

www.kgu.de/einrichtungen/institute/
zentrum-der-hygiene/medizinische-virologie/