Educational Program

Study program:

The PhD students in AVE are educated by a specific, however multidisciplinary curriculum. This allows them to answer urgent questions in the field of inflammation and its resolution. Besides a sound biomedical education in this field, key qualifications are creativity, independence, and the ability to solve problems as a member of a team. The structured curriculum in AVE is based on the long-standing expertise in post-graduate education within the faculties of Medicine and Pharmacy and is supported by a platform for doctoral education and research support provided at the University level by GRADE (more) and the GRADE Center ‘BioMed FIRST’ (more).

The study program consists of compulsory and voluntary parts that convey the theoretical and methodical basis to ensure an efficient and successful completion of PhD studies. This is accomplished by a tight supervision program, topic-centered lectures and seminars, as well as practical, methodological and soft skill courses.

AVE aims at educating its students to become experienced, well-trained, and independent figures in academia, the pharmaceutical industry, or in clinical practice.

Details of the curriculum offered by AVE are outlined below.

Seminars:

Every 2nd month

The graduate students organise a seminar series that takes place every second month. During the first year (seminar series 1) PhD students invite speakers, known for their contributions towards the topic “resolution of inflammation”. In the second and third year (seminar series 2) PhD students not only invite external guest speakers but also deliver short presentations on their own work. Following two PhD presentations, the external guest speaker and the PIs, discuss these results, which is followed by informal discussions with the guest speaker.

Date/Time Guest Speaker Lecture Title Location Download
23/11/2017
11:00 am
Prof. Dr. Dr.
Martin Herrmann
Medizinische Klinik 3
Universitätsklinikum Erlangen
Neutrophils in initiation
and resolution of inflammation
University Hospital
Bldg. 74, 4th floor
Room 4.107
23/01/2018
11:00 am
Dr. Claudia und
Prof. Marcel Nold
Hudson Institute of Medical
Research, Monash University
Clayton, Viktoria, Australia
tba University Hospital
Bldg. 74, 4th floor
Room 4.107

Lectures:

1st year, every 2nd week

During the first year of the educational program a special lecture series on topics related to resolution of inflammation will be organised, to provide a comprehensive overview of inflammatory pathways and its resolution. Thereby lectures given by the PIs touch on the different clusters of AVE and set the ground for the experimental work carried out by the PhD students. 26 individual lectures, each lasting 45 minutes, start with an introduction to inflammation, principals of innate and adaptive immunity, distinct forms of cell death, the relevance of endothelial and epithelial barriers, move to different forms of in vitro and in vivo inflammatory models, explain distinct signalling pathways and mediators being involved and address clinical symptoms of inflammation as well as therapeutic strategies.

Subjects:
  • An introduction to inflammation and its resolution
  • Macrophage polarization in inflammation and its resolution
  • Principles of innate immunity
  • Principles of adaptive immunity
  • The impact of cell death on immunity
  • Cancer and the resolution of inflammation
  • Inflammation at endothelial barriers
  • Pharmacology of classical anti-inflammatory drugs
  • Inflammation at epithelial barriers
  • Inflammatory diseases and models: Colitis
  • NF-κB family proteins in inflammation and its resolution
  • Innovative drugs for treating chronic inflammation
  • Specialized pro-resolving lipid mediators
  • New pharmacological strategies for resolution of inflammation
  • Eicosanoids in inflammation and its resolution
  • Inflammatory diseases and models: Atherosclerosis
  • Cytokines in inflammation and its resolution
  • Inflammatory diseases and models: Hepatitis
  • Mast cells in inflammation and its resolution
  • Inflammatory diseases and models: Peritonitis
  • ROS in inflammation and its resolution
  • Epigenetics of immunity and the resolution of inflammation
  • Translational regulation of inflammation and its resolution
  • Systems biology approaches to characterize inflammation
  • Inflammatory diseases and models: Psoriasis
  • Inflammatory diseases and models: Arthritis

Cluster Meetings:

Every month

Once a month the PhD students of each cluster will meet exclusively among themselves to discuss project related questions. Organisation and documentation of these meetings is the responsibility of the PhD students.

Workshops:

6 workshops/ three years

The graduate school members will attend six courses during their 3-year lasting PhD program, which comprises mandatory and elective courses. Workshops are either organised specifically for the PhD candidates or can be chosen from the various offers provided by GRADE (more).

The following list contains a selection of courses organised within AVE:

  • Project management
  • Teamwork and presentation skills
  • Statistics and data management
  • Ethical standards
  • Career planning
  • Elective courses

It is the intention that several courses are taken within the first year of the PhD education in order to provide basic skills for each person to guarantee a high success rate of their work.

Methods Internships:

Once a year

At least 3 courses during the entire PhD period are mandatory. It is the intention to provide insights in cutting edge scientific methodology, providing some ideas/overview how these methods are integrated into individual projects.

A list of potential courses is displayed below:

  • LC-MS/MS
  • Proteomics
  • Cell-Sorting
  • FACS
  • PhenOptics
  • MELK
  • NGS
  • Migration assays
  • Microscopy
  • 3D-Cellculture
  • Life Cell Imaging

Summer School:

3 days/ once a year

Summer schools take place once a year, lasting 3 days. During summer schools a special educational program will be provided and may comprise guided poster presentations, not only discussing scientific content of each individual project but also giving feedback to presentation standards and poster composition. In addition, there will be teaching courses on abstract writing, paper analysis, and workshops toward project development. During these international summer schools PhD students have the possibility to exchange ideas at an international level with students from Italy and Sweden.